Core Performance Comparison: Filtration Accuracy and Standards
HEPA Air Filters
Complying with international standards EN1822 and GB/T 6165, HEPA air filters achieve a filtration efficiency of 99.97% to 99.999% for particles measuring 0.3 microns (corresponding to H13–H14 grades). The tested particle size of 0.3 μm is defined as the "most penetrating particle size" (MPPS), meaning this efficiency value represents the minimum guaranteed performance.
ULPA Air Filters
ULPA air filters also conform to the EN1822 standard but offer exceptionally high efficiency in capturing finer particles as small as 0.12 μm, with a filtration rate of 99.9995% to 99.999995% (U15-U17 grades). They feature lower MPPS values and a more sophisticated structure, making them suitable for applications that require extremely stringent submicron particle control.
|
Parameter Type |
HEPA |
ULPA |
|
Filter level |
H13-H14 |
U15-U17 |
|
Test particle size(MPPS) |
0.3μm |
0.12μm |
|
Filtration efficiency |
99.97%-99.999% |
99.9995%-99.999995% |
Design and Process Differences
HEPA Filter Media Structure
Mostly composed of glass fiber or PP synthetic fiber, the interlaced fibers form a porous mesh structure that balances dust-holding capacity with low resistance.
ULPA Filter Media Structure
Made of finer PTFE composite membrane material with a denser fiber arrangement, ULPA filters must be assembled in a clean room environment. They feature an anti-static design and undergo leak detection on a unit-by-unit basis to eliminate any sealing defects.
Due to their higher structural density, ULPA filters typically have an initial resistance that is 30%–60% higher than that of HEPA filters, placing greater demands on fan performance and overall system energy consumption.
Analysis of typical application scenarios
|
Industry |
Recommended filters |
Reasons for use |
|
Semiconductors, Nanomaterials |
ULPA |
Prevent nano-sized particles from contaminating wafers or material surfaces |
|
Biosafety Laboratory |
ULPA |
Ensure zero leakage of pathogen particles |
|
Pharmaceutical aseptic filling line |
ULPA or H14 HEPA |
Select according to A/B level area requirements |
|
Hospital operating room, ICU |
H13/H14 HEPA |
Effectively filter bacteria and dust, balancing energy consumption and maintenance costs |
|
Food, General electronic assembly |
H13 HEPA |
Control micron-sized particles, cost-effective |
Selection Tips: ULPA air filter is recommended for cleanrooms of Class 5 and above as defined in ISO 14644-1; HEPA air filter can be used for Class 6-8
Life cycle cost comparison
|
Cost Items |
HEPA |
ULPA |
|
Purchase cost per unit |
Lower |
Higher |
|
Initial resistance |
Lower |
Higher |
|
System energy consumption |
medium |
Higher |
|
Maintenance cycle |
long |
short |
|
Service life |
1-2 years |
6-12 months |
Selection Decision Guide
Clearly define the cleanliness objective
Determine the allowable particle concentration and maximum particle size limit based on product processes or testing standards.
Evaluate system compatibility
Confirm whether the pressure-volume curve of the existing air-conditioning unit or fan filter unit (FFU) can support the higher resistance of a ULPA filter.
Calculate the total cost of ownership (TCO)
Beyond the initial purchase, consider electricity consumption, replacement frequency, and testing costs.
Focus on compliance and certifications
Choose suppliers with EN1822 certification and IEST-RP CC001/007 test reports.
Conclusion

Whether HEPA air filter or ULPA air filter, their shared goal is to ensure air cleanliness and protect both personnel and product safety. The main differences lie in filtration accuracy and applicable scenarios.
If your cleanroom requires extremely high particle control (such as in pharmaceutical or semiconductor production), ULPA is undoubtedly the best choice. For general cleanroom operations, HEPA offers a better balance between performance and cost.




























































