HEPA Vs ULPA Air Filters: How To Choose The Right One For Your Needs?

Oct 16, 2025

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Core Performance Comparison: Filtration Accuracy and Standards

 

HEPA Air Filters

Complying with international standards EN1822 and GB/T 6165, HEPA air filters achieve a filtration efficiency of 99.97% to 99.999% for particles measuring 0.3 microns (corresponding to H13–H14 grades). The tested particle size of 0.3 μm is defined as the "most penetrating particle size" (MPPS), meaning this efficiency value represents the minimum guaranteed performance.

ULPA Air Filters

ULPA air filters also conform to the EN1822 standard but offer exceptionally high efficiency in capturing finer particles as small as 0.12 μm, with a filtration rate of 99.9995% to 99.999995% (U15-U17 grades). They feature lower MPPS values and a more sophisticated structure, making them suitable for applications that require extremely stringent submicron particle control.

Parameter Type

HEPA

ULPA

Filter level

H13-H14

U15-U17

Test particle size(MPPS)

0.3μm

0.12μm

Filtration efficiency

99.97%-99.999%

99.9995%-99.999995%

 

 

Design and Process Differences

 
01/

HEPA Filter Media Structure

Mostly composed of glass fiber or PP synthetic fiber, the interlaced fibers form a porous mesh structure that balances dust-holding capacity with low resistance.

02/

ULPA Filter Media Structure

Made of finer PTFE composite membrane material with a denser fiber arrangement, ULPA filters must be assembled in a clean room environment. They feature an anti-static design and undergo leak detection on a unit-by-unit basis to eliminate any sealing defects.

Due to their higher structural density, ULPA filters typically have an initial resistance that is 30%–60% higher than that of HEPA filters, placing greater demands on fan performance and overall system energy consumption.

 

 

Analysis of typical application scenarios

 

 

Industry

Recommended filters

Reasons for use

Semiconductors, Nanomaterials

ULPA

Prevent nano-sized particles from contaminating wafers or material surfaces

Biosafety Laboratory

ULPA

Ensure zero leakage of pathogen particles

Pharmaceutical aseptic filling line

ULPA or H14 HEPA

Select according to A/B level area requirements

Hospital operating room, ICU

H13/H14 HEPA

Effectively filter bacteria and dust, balancing energy consumption and maintenance costs

Food, General electronic assembly

H13 HEPA

Control micron-sized particles, cost-effective

Selection Tips: ULPA air filter is recommended for cleanrooms of Class 5 and above as defined in ISO 14644-1; HEPA air filter can be used for Class 6-8

 

 

Life cycle cost comparison

 

 

Cost Items

HEPA

ULPA

Purchase cost per unit

Lower

Higher

Initial resistance

Lower

Higher

System energy consumption

medium

Higher

Maintenance cycle

long

short

Service life

1-2 years

6-12 months

 

 

Selection Decision Guide

 
01.

Clearly define the cleanliness objective

Determine the allowable particle concentration and maximum particle size limit based on product processes or testing standards.

02.

Evaluate system compatibility

Confirm whether the pressure-volume curve of the existing air-conditioning unit or fan filter unit (FFU) can support the higher resistance of a ULPA filter.

03.

Calculate the total cost of ownership (TCO)

Beyond the initial purchase, consider electricity consumption, replacement frequency, and testing costs.

04.

Focus on compliance and certifications

Choose suppliers with EN1822 certification and IEST-RP CC001/007 test reports.

 

 

Conclusion

 

 

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Whether HEPA air filter or ULPA air filter, their shared goal is to ensure air cleanliness and protect both personnel and product safety. The main differences lie in filtration accuracy and applicable scenarios.

If your cleanroom requires extremely high particle control (such as in pharmaceutical or semiconductor production), ULPA is undoubtedly the best choice. For general cleanroom operations, HEPA offers a better balance between performance and cost.

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